Beta3-Integrin Protein Continues to be Important in Cancer Research

by Kathy Jones on  January 7, 2014 at 7:46 PM Cancer News
RSS Email Print This Page Comment
New research from the University of East Anglia (UEA) indicates that a protein which has been at the forefront of cancer drug research over the last two decades continues to be important in the overall scenario.
 Beta3-Integrin Protein Continues to be Important in Cancer Research
Beta3-Integrin Protein Continues to be Important in Cancer Research
Advertisement

Recently, the latest version of the drugs made from the protein called αvβ3-integrin antagonists failed to meet targets in treating aggressive forms of brain cancer. However, the current study says that it is too early to give up on the protein as other drugs cause unpleasant side-effects such as bleeding from the gut and high blood pressure.

Advertisement
"This research helps to explain why these very promising drugs aren't meeting with the success that was anticipated and it suggests a way forward - how to make them work better," said Dr Stephen Robinson, from UEA's school of Biological Sciences. "We have identified some molecular changes in endothelial cells that occur with long-term inhibition of beta3-integrin that might help the cells escape the beta3-integrin blockade. Our research also shows that timing is critical when targeting the protein beta3-integrin."

The study details appear in the journal Circulation Research.



Source: Medindia
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Cancer and Homeopathy Cancer Facts Cancer Tattoos A Body Art Magical Millets for Your Health The Basics of Baby Food Diet and Nutrition Tips for Athletes Nutrition IQ Common Lifestyle Habits that Cause Diseases Health Benefits of Dandelion Plant 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive