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Aphthous Ulcers: Mucosal Inflammation With Unclear Causes

by Himabindu Venkatakrishnan on  October 23, 2014 at 8:46 AM General Health News   - G J E 4
Aphthous ulcer has occurred in every third individual, at some point of time. It is a painful inflamed lesion on the oral mucosa that often seems to be burning at the periphery.
 Aphthous Ulcers: Mucosal Inflammation With Unclear Causes
Aphthous Ulcers: Mucosal Inflammation With Unclear Causes
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Often they resolve after a brief period of time. In 2% to 10% of patients these lesions are recurrent and require medical treatment. Unfortunately, as Andreas Altenberg and co-authors point out in a current review on the therapy of aphthous ulcers (Dtsch Arztebl Int 2014; 111: 665-73), the etiology of these lesions is unclear.

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Thus aphthous ulcers can only be treated symptomatically.Even though we do not know how aphthous ulcers develop, a number of predisposing factors have been identified: iron, folic acid and vitamin B12 deficiency as well as mucosal injuries can lead to aphthous ulcers. Patients are advised as a prophylactic measure to avoid firm, acidic and salty foods, alcohol and carbonated beverages. According to the authors, most cases should be treated with a topical agent, usually an ointment. Only in severe forms of the disease is the use of systemic medications necessary.

Source: Eurekalert
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