Antibiotic Resistance may be Overcome by Disarming Bugs

by Kathy Jones on  April 7, 2012 at 2:36 PM Drug News
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A new study has said that disarming harmful bugs rather than trying to kill them may help overcome antibiotic resistance.

Research led by Monash University in Melbourne, Australia showed a protein complex called TAM formed a type of molecular pump in bacteria.
 Antibiotic Resistance may be Overcome by Disarming Bugs
Antibiotic Resistance may be Overcome by Disarming Bugs

The pump allows bugs to shift disease-causing molecules from inside the bug cell to the outside, readying them for infection, the journal Nature Structure and Molecular Biology reports.

Biochemistry doctoral student Joel Selkrig at Monash University, who led the study, said the work opens the way to developing new drugs that disrupts the pumping process, neutralising the bugs potential to infect, according to a Monash statement.

"The TAM was discovered in many disease-causing bacteria that cause whooping cough and meningitis, to hospital-acquired bacteria that are developing resistance to current antibiotics," Selkrig said.

Source: IANS

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