Sugary Drinks Increase Risk of Diabetes, Heart Disease and Stroke
Drinking soda or juices regularly were found to be associated with metabolic syndrome, heart disease, stroke, diabetes, and high blood pressure.
Drinking soda or juices regularly were found to be associated with metabolic syndrome, heart disease, stroke, diabetes, and high blood pressure.
‘Over time, having too much glucose in your blood can cause health problems. Although diabetes has no cure, you can take steps to manage your diabetes and stay healthy.’
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"First we had hoped that we would be able to replicate the findings, but they didn't hold up," said Mark Huising, in the Department of Neurobiology, Physiology and Behavior, UC Davis College of Biological Sciences. "People with Type 1 diabetes, they see these stories come out and they think maybe there's something on the horizon and then nothing ever follows through," Huising said. Understanding diabetes at the cellular level
The symptoms of Type 1 and Type 2 diabetes are quite similar but the underlying causes differ. In type 1 diabetes, the body fails to create enough insulin, a hormone produced by the pancreas that regulates cellular intake of nutrients. In Type 2 diabetes, cells no longer respond efficiently to insulin.
High Rate of Needle Reuse Among Diabetes Patients in India
Some people with diabetes use their insulin syringes more than once to save money. But makers of syringes do not recommend using them more than once.
Some people with diabetes use their insulin syringes more than once to save money. But makers of syringes do not recommend using them more than once.
"That's the cell that if you lose (insulin production), you get Type 1 diabetes," said Huising. So there is always interest in any process that might generate new beta cells to replace those lost in Type 1 diabetes.
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Obesity and Diabetes Rates High Among Neglected Groups
Understudied racial minority groups in U.S show alarmingly high rates of obesity and diabetes than non-Hispanic white adults, research revealed.
Understudied racial minority groups in U.S show alarmingly high rates of obesity and diabetes than non-Hispanic white adults, research revealed.
In early 2017, in a paper published in the journal Cell, a European team reported that the antimalarial drug artemether could convert alpha cells into functional beta cells. While alpha cells converting into beta cells had been described before, this was the first time an existing drug had been reported to stimulate the process and it caused a lot of excitement in the field, Huising said.
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Insulin Sensitizers Without Side Effects For Diabetes Management
Drugs that improve insulin sensitivity can also increase lipid levels. Developing molecules that does not affect lipid levels can be developed.
Drugs that improve insulin sensitivity can also increase lipid levels. Developing molecules that does not affect lipid levels can be developed.
"We were hoping, expecting, to confirm," Huising said. "We weren't able to."
The importance of reproducibility
For her experiments, Lee used pancreatic islets derived from mice. After around four months of experiments with artemether, it was clear that the drug was not triggering alpha to beta cell conversion, as the initial Cell paper had claimed.
Lee and Huising's paper highlights the importance of reproducibility, a perennial and hotly contested topic of concern at all levels of scientific research. It also demonstrates how routine lab assignments meant to educate students can provide the foundations for published research.
"It's important to realize that our work has an impact in the real world," Huising said. "We should continuously strive to hold ourselves and our peers to a higher standard, particularly when we talk about discoveries that promise a possible cure for diabetes."
Source-Eurekalert
