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Anti-Amyloid-Beta Antibodies can Improve Memory Performance in Alzheimer's Disease Patients

by Bidita Debnath on  January 7, 2014 at 10:46 PM Research News   - G J E 4
Amyloid-beta assemblies may be one of the most important causes of Alzheimer's disease earlier.

Passive immunization of anti-amyloid-beta antibodies can reduce amyloid-beta burden and improved memory performance in various Alzheimer's disease animal models or patients.
 Anti-Amyloid-Beta Antibodies can Improve Memory Performance in Alzheimer's Disease Patients
Anti-Amyloid-Beta Antibodies can Improve Memory Performance in Alzheimer's Disease Patients
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Screening humanized antibodies from a human Fab phage display library is an effective and quick method to obtain beta-amyloid oligomers. Thus, a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013) successfully constructed a na´ve human Fab library and obtained a human Fab antibody and a single-domain antibody that specifically recognized amyloid-beta (Aβ)42 oligomers.

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Source: Eurekalert
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