Dimebon (latrepirdine), a pill being developed for Alzheimer's disease, has been found to improve mental abilities in some patients with Huntington's disease, says a new study.
The research has been published in the Archives of Neurology.
Molecular Switch to Prevent Huntington's Disease Found
American researchers have discovered a molecular switch to prevent Huntington's disease from developing in mice.
American researchers have discovered a molecular switch to prevent Huntington's disease from developing in mice.
Huntington's disease is a progressive neurodegenerative disorder that impacts movement, behavior, cognition, and generally results in death within 20 years of the disease's onset. The disease steadily erodes a person's memory and their ability to think and learn. Over time, this cognitive impairment contributes to the loss of the ability to work and perform the activities of daily life. There are no treatments current available that effectively alter the course of the disease or improve cognition.
It is believed that mitochondria - the part of the cell that helps convert food to energy - plays a role in the development of Huntington's disease. Lampridine stabilizes and enhances mitochondrial function, a result that has been shown to improve behavioral, cognitive, and functional outcomes in Alzheimer's disease. Scientists speculate that this may have the same effect in patients with Huntington's disease.
Huntington's Disease is Inhibited as Well as Promoted by IKK
A new study has found that the kinase IKK phosphorylates the protein mutated in Huntington's disease to promote its removal and neuron survival
A new study has found that the kinase IKK phosphorylates the protein mutated in Huntington's disease to promote its removal and neuron survival
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Potential Treatment for Huntington's Disease Found
Discovering a potential new treatment for Huntington's disease, researchers have found that normal synaptic activity in nerve cells protects the brain from the misfolded proteins
Discovering a potential new treatment for Huntington's disease, researchers have found that normal synaptic activity in nerve cells protects the brain from the misfolded proteins
Gene Therapy can be Used to Halt Huntington's Disease
Scientists from California Institute of Technology (Caltech) have suggested a gene therapy that is capable of stalling the development of Huntington's disease.
Scientists from California Institute of Technology (Caltech) have suggested a gene therapy that is capable of stalling the development of Huntington's disease.
