A Quantum Leap in Gene Therapy

by Bidita Debnath on  January 16, 2013 at 11:16 PM Research News
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Normally, results from a new study help scientists inch their way toward an answer whether they are battling a health problem or are on the verge of a technological breakthrough.
 A Quantum Leap in Gene Therapy
A Quantum Leap in Gene Therapy

Once in a while, those results give them a giant leap forward. In a preliminary study in a canine model of Duchenne muscular dystrophy (DMD), University of Missouri scientists showed exactly such a leap using gene therapy to treat muscular dystrophy. The results of the study will be published in the journal Molecular Therapy on Jan. 15, 2013.

Muscular dystrophy occurs when damaged muscle tissue is replaced with fibrous, bony or fatty tissue and loses function. Duchenne muscular dystrophy is the most common type of muscular dystrophy predominantly affecting boys. Patients with DMD have a gene mutation that disrupts the production of dystrophin, a protein essential for muscle cell survival and function. Absence of dystrophin starts a chain reaction that eventually leads to muscle cell degeneration and death. For years, scientists have been working to find the key to restoring dystrophin, but they have faced many challenges.

Source: Eurekalert

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