Most Popular on Medindia

P
M

A Detailed Map Of Neural Connections in Human Brain Is Being Developed by Scientists

by Rukmani Krishna on  September 17, 2013 at 12:30 AM General Health News   - G J E 4
Scientists have been working tirelessly to build a detailed map of neural connections in the human brain---- with the ultimate hope of understanding how the mind works. In the past few years, imaging tools and techniques have improved.
 A Detailed Map Of Neural Connections in Human Brain Is Being Developed by Scientists

But determining how cells in the brain are physically connected is only the first clue for decoding our perceptions and behaviors. We also need to know the precise routes that information takes in the brain in a given context. Now, publishing their results September 8 in the journal Nature Neuroscience, researchers at the Salk Institute for Biological Studies have shown a striking example of the flexibility in neural circuitry and its influence on behaviors in worms, depending on the animals' environment.

The roundworm Caenorhabditis elegans has exactly 302 neurons----far less than the estimated 100 billion neurons a person has----and we already know how each of them is connected. That, in addition to how easily the tiny creature's cells can be manipulated, allows researchers to ask what sort of information passes through the circuits----in molecular-and circuit-level detail----and what are the behavioral consequences of this information flow.

Even with a comprehensive map of the worm's neuronal connections in hand, however, scientists still don't know how the animal can interact with its environment in thousands of different ways. That's one big question that Sreekanth Chalasani, an assistant professor in Salk's Molecular Neurobiology Laboratory and Sarah Leinwand, a doctoral student at the University of California, San Diego, sought to answer.

In C. elegans, thanks to studies performed more than 20 years ago, many sensory neurons were identified to have distinct roles such as sensing temperature, pheromones, salt and odors. To know what these cells did, scientists had zapped them one-by-one with a laser and measured the worms' behaviors. These studies implicated one neuron in the detection of increased salt in the worm's surroundings.

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

Ask an Expert

C
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
X

Ask an Expert

Ask an Expert+
s
Study Says Binge Drinking Common Among US Teens
 Study Says Binge Drinking Common Among US Teens
S  Medical Advances, Better Treatment And New Drugs Help An Average American To Live 3.8 Years Longer
Medical Advances, Better Treatment And New Drugs ...