Eight out of 10 people say it was women who were responsible for starting any trouble in the family, a new Brit survey has found.
And mothers are the relatives we are most likely to fall out with, their survey revealed.
The arguments are most likely to be over lending money, favouritism and disliking a relative's partner. And while most fights get resolved within a year, one in five has gone more than three years without talking to a loved one - and one in 10 has refused to speak for more than 20 years.
The study also revealed that a third of Britons would call their families "dysfunctional".
A third had gone for periods of time not talking to their mothers. Fathers were in second place when it comes to the relatives we are most likely to fall out with, followed by sisters.
The figures emerged in a survey of 3,000 adults by Twentieth Century Fox Home Entertainment to celebrate the launch of Family Guy Season 9.
"Although mums were the family members we were most likely to fall out with, the study showed that women were much more likely to recognise if their family behaved dysfunctionally and if there were problems in the family," The Daily Express quoted a spokesman for Fox as saying.