Women May Find Protection from Endometrial Cancer from Diabetes Drug

by Tanya Thomas on  April 10, 2011 at 10:16 AM Women Health News
RSS Email Print This Page Comment
Metformin, a drug used to treat diabetes and also women with Polycystic Ovary syndrome (PCOS), may potentially provide protection against endometrial cancer, researchers at the University of Warwick have found.
 Women May Find Protection from Endometrial Cancer from Diabetes Drug
Women May Find Protection from Endometrial Cancer from Diabetes Drug
Advertisement

Endometrial cancer is the most common malignancy of the female genital tract and the fourth most common cancer in women in the UK and the US.

Advertisement
Recent research has found that Metformin has anti-cancer properties e.g. in breast cancer. Given that insulin resistant states, e.g. obesity, diabetes and PCOS are more at risk of developing endometrial cancer, the Warwick researchers studied the effects of metformin treatment on endometrial cancer cells. The researchers used serum from control and PCOS (before and after metformin treatment) subjects and carried out basic scientific experiments on endometrial cancer cells. The experiments revealed a decrease in endometrial cancer cell invasiveness in sera from metformin treated PCOS women.

The researchers found that serum samples from PCOS women who had completed the 6 month course of Metformin the rate of spread of endometrial cancer cells was around 25 pc lower than in the serum samples from PCOS women who had not started that treatment.

"We are very excited about our findings, which reveal the significant impact of Metformin therapy use on human endometrial cancer cells. However, it is prudent that further research to explore if Metformin would actually be beneficial clinically as adjuvant therapy in endometrial cancer; this would need to be addressed through a randomized controlled trial," said the principal investigators, Harpal Randeva and Bee K Tan, at Warwick Medical School.

The research paper has been published in The Journal of Clinical Endocrinology and Metabolism.

Source: ANI
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions
caringstd66 Monday, April 11, 2011

One of my friends got Genital herpes many years. he knew how difficult to find support, love or friendship. To help more people living with STDs, we launched STDdatings.com in 2001, the exclusive STD support site serving poz people with Herpes[HSV 1,HSV 2],HIV,HPV,Hepatitis. No rejection or discrimination. If you or someone you know is living with STDs, please come visit our site and add us as friend. Never live in your own dark corner.

Related Links

More News on:

Women and Cancer Diabetic Retinopathy Drug Toxicity Diabetes Diabetic Diet Diabetes - Essentials Cancer and Homeopathy Diabetes - Self-Monitoring of Blood Glucose (SMBG) Insulin Delivery Devices Dilatation and Curettage 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive