Will Resting Brains Could Offer Clues to Mental Health Disorders?

by Sreeraman on  May 10, 2009 at 1:40 PM Research News
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Hoping to some day develop new tools for diagnosing mental health disorders and monitoring the progress of their treatments, scientists have now turned to uncovering new information about the mind by studying brains while they are at rest.

Researchers at Oregon Health and Science University are running one such research project in collaboration with experts at Washington University in St. Louis, the latest findings of which have been published in the journal the Public Library of Science Computational Biology.

"For years, the vast majority of scientists studying human functional brain organization have focused on how activity changes when engaged in specific tasks," said Dr. Damien Fair, a postdoctoral research scientist in psychiatry, OHSU School of Medicine.

"However now we know there are several regions in the brain that continue to interact while a person is supposedly at rest - sort of like a car that idles at a stoplight. Our lab is studying these interactions, or spontaneous brain activity, while the brain is at rest. We think that this approach will eventually help us distinguish typical function from atypical function and therefore help more rapidly diagnose and appropriately treat mental disorders," the researcher said.

The researchers use a form of magnetic resonance imaging (MRI), known as functional connectivity MRI, to study the brains of a large group of subjects while they were at rest.

The researchers said that their efforts led to the identification of brain regions that spontaneously activated together while the subjects were at rest.

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