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Why Humans Outlive Apes: Study
The genetic adaptation that increases human lifespan is also responsible for making us uniquely susceptible to diseases of aging such as cancer, heart disease and dementia, revealed the study.
Caleb Finch, ARCO and William F. Kieschnick Professor in the Neurobiology of Aging, compared the life spans of humans with other primates.
And they explained that slight differences in DNA sequencing in humans have enabled us to better respond to infection and inflammation- the leading cause of mortality in wild chimpanzees and in early human populations with limited access to modern medicine.
Specifically, humans have evolved what Finch calls "a meat-adaptive gene" that has increased the human lifespan by regulating the effects of meat-rich diets.
ApoE3 is unique to humans and is a variant of the cholesterol transporting gene, apolipoprotein E, which regulates inflammation and many aspects of aging in the brain and arteries.
"Over time, ingestion of red meat, particularly raw meat infected with parasites in the era before cooking, stimulates chronic inflammation that leads to some of the common diseases of aging," said Finch.
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