Why Do Promising Clinical Trials Fail?

by Rathi Manohar on  March 15, 2011 at 12:15 PM Clinical Trials News
RSS Email Print This Page Comment bookmark
Font : A-A+

Failed clinical trials happen when optimistic predictions about human trials are made from animal studies of a new drug, claim experts.
 Why Do Promising Clinical Trials Fail?
Why Do Promising Clinical Trials Fail?

Ethics experts Jonathan Kimmelman, associate professor at McGill's Biomedical Ethics Unit and Department of Social Studies of Medicine, Montreal; and Alex John London, associate professor of philosophy at Carnegie Mellon University, Pennsylvania, examined a string of failed clinical trials and they come to the conclusion that researchers base their predictions on successful pre-clinical studies done on animals. But when, later on, human trials are involved, the new drug fails.

'We also need to look at how similar interventions have fared in the past,' Dr London said. 'If drugs that work on the same principle have failed development, there may be good grounds for tempering expectations.'

The researchers recommended that techniques used in clinical trials, such as randomisation and blind testing, should also be used in the design of pre-clinical trials too.



Source: Medindia

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Clinical Trials Clinical Trials - The Past and The Future Clinical Trials - Different Phases of the trial Placebo Effects: Rare Insights 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive