Vulnerability to PTSD, Depression and Anxiety may be Inherited

by Sreeraman on  December 21, 2008 at 10:49 AM Mental Health News
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"That tracks with clinical experience. For example, in clinical practice, the therapist will often discover that patients who come in for treatment of depression have coexisting anxiety. Our findings show that a substantial portion of the coexistence can be explained on the basis of shared genes and not just environmental factors such as upbringing," he said.

The study involving statistical methods to assess heritabilities showed that that a significant amount of genes were shared between PTSD and depression, PTSD and anxiety, and finally depression and anxiety.

Goenjian claimed that this is the first time that a study suggesting such a heritability of PTSD has been based on whole families, who were exposed to a particular trauma like earthquake.

He said all previous studies showing such results had been twin studies.

"It's very hard to do family studies on PTSD because typically only single individuals, not whole families, are exposed to a particular trauma. In our study, we were able to avert this problem since all the subjects were exposed to the same severe trauma at the same time," he said.

Goenjian said that the findings were promising for the next step in understanding the underlying biology of such disorders, that is, locating the specific genes involved.

Source-ANI
SRM
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