Low levels of vitamin D are linked to lower lung function and greater medication use in children with asthma, according to a study.
Researchers, led by Dr. Daniel Searing at National Jewish Health, also reported that vitamin D enhances the activity of corticosteroids, the most effective controller medication for asthma.
"Asthmatic children in our study who had low levels of vitamin D were more allergic, had poorer lung function and used more medications. Conversely, our findings suggest that vitamin D supplementation may help reverse steroid resistance in asthmatic children and reduce the effective dose of steroids needed for our patients," said Searing.
The researchers analysed electronic medical records of 100 pediatric asthma patients referred to National Jewish Health.
Overall, 47 percent of them had vitamin D levels considered insufficient, below 30 nanograms per milliliter of blood (ng/mL).
Seventeen percent of the patients had levels below 20 ng/mL, which is considered deficient.
The levels were similar to vitamin D levels found in the general population.
Patients low in vitamin D generally had higher levels of IgE, a marker of allergy, and responded positively to more allergens in a skin prick test. Allergies to the specific indoor allergens, dog and house dust mite, were higher in patients with low vitamin D levels.