Vitamin D Deficiency Linked With Lung Transplant Rejection

by VR Sreeraman on  October 19, 2010 at 4:50 PM Organ Donation News
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 Vitamin D Deficiency Linked With Lung Transplant Rejection
A research conducted at Loyola University Health System (LUHS) has revealed that vitamin D deficiency is associated with a significant increase in lung transplant rejection.

"Vitamin D deficiency is prevalent among lung transplant recipients," said Pauline Camacho, MD, study investigator and director of the Loyola University Osteoporosis and Metabolic Bone Disease Center.

"This study shed greater light on the serious impact that this deficiency has on lung transplant patients," he said.

Patients who undergo lung transplants are at risk for rejecting the organ, and 77 percent of these patients are vitamin D deficient.

Researchers believe that vitamin D helps the immune system tolerate the organ. Thus optimal levels of this supplement are critical for positive outcomes.

This study evaluated 122 patients who underwent a lung transplant at Loyola between January 2005 and June 2008. Sixty-four patients were male and 58 were female with an average age of 49.2 years.

Vitamin D levels were checked following the transplants. Of the 122 patients, 50 percent were vitamin D deficient, 18 percent were not deficient and 32 percent were unknown.

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