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Vitamin D Aids Faster Recovery From TB

by Savitha C Muppala on  January 7, 2011 at 8:58 PM Research News   - G J E 4
Scientists at Barts and The London School of Medicine and Dentistry have found that Vitamin D can help antibiotic treatment of tuberculosis (TB).
 Vitamin D Aids Faster Recovery From TB
Vitamin D Aids Faster Recovery From TB
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During the study led by Dr Adrian Martineau of the Centre for Health Sciences at Barts and The London School of Medicine and Dentistry, 146 patients with drug-sensitive TB were evenly assigned four oral doses of 2.5 mg of Vitamin D, or a placebo. The standard antibiotic treatment for the condition also continued undisturbed for all the participants.

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It takes up to six weeks for clearance of TB from the lungs and all those on standard therapy stuck to the estimated recovery time. Those participants, who took Vitamin D in addition to the standard therapy, seemed to recover within 5 weeks itself. The difference in recovery time may not be that significant, yet it was seen that patients with a specific genetic type of Vitamin D receptor responded faster to standard antibiotic treatment for clearing TB when they received Vitamin D.

In the words of lead researcher Dr Adrian Martineau, 'Vitamin D is best known for its effects on bones - it prevents rickets and osteomalacia - but it also has important effects on the immune system. High dose vitamin D was used to treat TB in the days before antibiotics were available, but clinical trials have not previously been performed to find out how TB patients' genetic make-up can affect their response to vitamin D supplementation. The finding that patients who have a particular type of vitamin D receptor are very responsive to vitamin D is new and gives us insights into how vitamin D can affect the immune response.'



Source: Medindia
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