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Vaccines On Your Plate
June 12, 2007 at 5:15 PM
Genetics & Stem Cells News
It is widely recognized that an effective mucosal vaccine would probably offer the best protection against infections such as cholera, Escherichia coli, HIV, influenza and SARS.
One of the big hurdles in the way of developing easy to administer edible vaccines is that they tend to be destroyed by digestive enzymes. Another obstacle to large-scale immunization in the developing world is the cost of storage. Traditional vaccines cannot be stored at room temperature, and the worldwide cost of refrigerating them is put at between Ģ101 million and Ģ152 million a year.
The new vaccine is said to solve both problems. In tests it was resistant to the digestive enzyme pepsin, and it remained stable at room temperature for more than 18 months.
The Japanese researchers say that the cholera vaccine bound within the rice can be stored at room temperature over long periods and is immune to digestion. They believe such rice vaccines could in future protect large populations against a wide range of infectious diseases.
Source-Medindia
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