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US and Arab Researchers Seeking Gene Therapy For Blindness
The therapy has been shown to restore lost vision in animal models of retinitis pigmentosa (RP).
The RP patients first experience defective dark adaptation or "night blindness," followed by reduction of the peripheral visual field known as tunnel vision, sometimes followed by loss of central vision late in the course of the disease.
The team led by Dr Kang Zhang, professor of ophthalmology at the University of California, San Diego School's Shiley Eye Center and director of the UCSD Institute for Genomic Medicine, and Dr Fowzan Alkuraya, senior clinical scientist and head of developmental genetics unit at King Faisal Specialist Hospital and Research Centre, Saudi Arabia are using receptor protein called MERTK that is expressed in the retinal pigment epithelium,
It is the pigmented cell layer just outside the retina that closely interacts with photoreceptors in the maintenance of visual function.
Patients with loss of MERTK function have a defect in phagocytosis - a mechanism used to remove pathogens and cell debris.
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More News on: DNA Finger Printing, Reiki and Pranic Healing, Genetic Testing of Diseases, Pancreas, Blindness Facts, Niemann-Pick Disease
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anupankaj(Guest)
08/05/2009
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Please hurry up I don't want to be blind.