US Company Could Make Flu Vaccine Abroad After Snub

by Sreeraman on  November 22, 2009 at 12:15 PM Drug News
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But the egg-based technology is outdated, inefficient and vulnerable to a complete breakdown in the event that bird flu should sweep across the United States, just as swine flu has this year.

A massive campaign to vaccinate millions of Americans against swine flu has been hampered by a severe shortage of vaccine, and that has been blamed in part on the slow rate at which the (A)H1N1 virus grows in eggs.

Lawmakers have questioned whether vaccine production has also been held up by the fact that only one of the five companies producing flu vaccine does so in the United States.

Protein Sciences said its vaccine could be rolled out within 75 days after the start of development.

Theodore Eickhoff of the University of Colorado said at Thursday's meeting that the Protein Sciences vaccine had a huge advantage over chicken-egg-based vaccine because it can be produced quickly.

"This would have been a breakthrough for the United States and it would certainly have been helpful to have this available this fall," said Eickhoff, who was largely in favor of recommending that the FDA license the new-technology vaccine.

The panel did praise the nimbleness of Protein Sciences' vaccine production method, saying it would allow the United States to "move quickly when we need to."

But the vaccine stumbled and fell at the jump on safety concerns, and the panel asked Protein Sciences to come back at a later date with more data.

"Clinical trials of our swine flu vaccine went very well in Australia. What can I say? We will probably do licensure in Australia," said Cox.

Source-AFP
SRM
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