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The Wait is Over - Nobel Prize for Medicine 2011 Announced
This year, one half of the Nobel for Medicine has gone to Bruce A. Beutler and Jules A. Hoffmann "for their discoveries concerning the activation of innate immunity." They discovered proteins that could identify micro organisms and activate innate immunity. This is the first step towards an immune response.
The other half of the prize has gone t to Ralph M. Steinman "for his discovery of the dendritic cell and its role in adaptive immunity." Steinman discovered the dendritic cells of the immune system and studied their role in adaptive immunity which is actually a later- stage immune response.
From Fundamental Research to Medical Use
The discoveries that are awarded the 2011 Nobel Prize have provided novel insights into the activation and regulation of our immune system. They have made possible the development of new methods for preventing and treating disease, for instance with improved vaccines against infections and in attempts to stimulate the immune system to attack tumors. These discoveries also help us understand why the immune system can attack our own tissues, thus providing clues for novel treatment of inflammatory diseases.
Bruce A. Beutler was born in 1957 in Chicago, USA. He received his MD from the University of Chicago in 1981 and worked as a scientist at Rockefeller University in New York and the University of Texas in Dallas, where he discovered the LPS receptor. Since 2000 he has been professor of genetics and immunology at The Scripps Research Institute, La Jolla, USA.
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10/04/2011
The sad part is Ralph Steinman died before the award was announced.
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