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The Protein That Warns the Liver That Fatty Cheese Burger is on Its Way
"The good news is that when you provide a synthetic version of the peptide, it reverses some of the consequences of obesity," he said.
Now the researchers want to know whether mice that lack adropin become obese and show evidence of the metabolic syndrome, a cluster of diseases associated with obesity and insulin resistance.
Also, the protein is even produced in the brain, indicating it may also affect behaviour and metabolism in as-yet-undiscovered ways.
However, researchers are still not sure how adropin works its magic. They said that its benefits could involve effects within the liver and/or hormonal actions on other body tissues.
"In summary, adropin is a newly discovered secreted peptide that is involved in energy homeostasis and lipid metabolism ... Adropin may form the basis for the development of new therapeutic targets for treating metabolic disorders associated with obesity," wrote the researchers.
The study is published in the latest issue of the journal Cell Metabolism, a Cell Press publication.
Source-ANI
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Roop80(Guest)
12/05/2008
Adropin and its role in liver metabolism was published by K Ganesh Kumar and co-workers in latest issue of Cell metabolism. It is a break through discovery and this can be a therapeutic target for obesity related metabolic disorders
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