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The 'Cruciferous' Boost To Aging Immune System
The boffins found that broccoli and other such vegetables have a chemical called sulforaphane that could hold a key to restoring the body's immunity, which declines as people grow older.
According to the study, sulforaphane interacts with a protein called Nrf2, which serves as a master regulator of the body's overall antioxidant response.
This particular protein is capable of switching on hundreds of antioxidant and rejuvenating genes and enzymes in specific immune cells. These cells then fight the injurious effects of free radicals - molecules that can damage cells and lead to disease.
The study on mice was led by Dr. Andre Nel, chief of nanomedicine at the David Geffen School of Medicine at UCLA, and concentrated on pathways used by the body to suppress the production of free radicals.
"Our study contributes to the growing understanding of the importance of these antioxidant defense pathways that the body uses to fight free radicals," said Nel, a practicing clinical allergist and immunologist at the Geffen School.
"Insight into these processes points to ways in which we may be able to alleviate the effects of aging.
"As we age, the ability of the immune system to fight disease and infections and protect against cancer wears down as a result of the impact of oxygen radicals on the immune system."
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