The Ageing Human Kidney's Genetic Link Identified


Advertisement
by Tanya on  October 19, 2009 at 10:53 AM Research News
  •   Print
  •   Share
  •   Comments
  •  Text 
 The Ageing Human Kidney's Genetic Link Identified
In a novel study, researchers claim to have identified a gene linked to human kidney aging.

Kidneys age at different rates, such that some people show little or no effects of kidney aging whereas others show rapid functional decline.

Determining genetic factors associated with different rates of kidney aging can help researchers understand the molecular mechanisms underlying human aging process.

Lead researcher Dr. Stuart Kim used genome-wide transcriptional profiling to determine that 630 genes change expression with age in kidney tissue.

They further found that 101 of these age-regulated genes contain DNA variations among individuals that associate with gene expression level. gene that encodes an extracellular matrix protein (MMP20) was revealed to be significantly associated with kidney aging, providing the first gene association with kidney aging.

The researchers suggest that more aging genes are discovered and confirmed, the particular genetic variants belonging to a person could one day be combined to better predict the aging trajectory of the kidney.

The study appears in PLoS Genetics.

Source-ANI
TAN
Do you like this Report?
0

 Email Email  RSS Feeds RSS Feeds  Print this page Print  Save this page Save  Link Link  Syndicate Syndicate  Comments Comments 
 
Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions
  
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
X

Related Links

Research Related News

Medwonders Health Network

  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Archive
Date :
Category :
Keyword :
Quiz on Ageing
Curious about old age? Go through our Ageing quiz to find out more.
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
News Categories:  
Senior Health Center