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Tamiflu Still Number One In Treatment Of Bird Flu
August 25, 2007 at 6:10 PM
Bird Flu News
“Experiences clearly show that to reduce mortality patients should receive treatment with oseltamivir as early as possible, but treatment remains effective even when patients present late,” commented Professor John Oxford, Professor of Virology at St Bartholomew’s and the Royal London Hospital, “H5N1 has proven to be an extremely virulent virus in humans and in some countries we have seen the need to use higher and longer doses of oseltamivir to gain maximum benefit.”
The latest advice is based on evidence presented to the WHO by experts in countries that have reported human cases of bird flu. Tamiflu is the only neuraminidase inhibitor to have been used in the management of human cases of H5N1 and is the only antiviral strongly recommended for treatment of H5N1 infected patients by the WHO.
With this latest evidence WHO recommends:
Standardising care and promptly sharing clinical and treatment information to improve understanding of the disease and identify appropriate therapy.
Tamiflu remaining the primary antiviral treatment both early and late in the infection as there is evidence of prolonged replication with H5N1.
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