Sugar In Breast Milk Promotes Colitis In Offspring In Later Life

by VR Sreeraman on  November 23, 2010 at 6:44 PM Research News
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New research has revealed that a sugar found in mouse breast milk promotes the generation of colitis in offspring.
 Sugar In Breast Milk Promotes Colitis In Offspring In Later Life
Sugar In Breast Milk Promotes Colitis In Offspring In Later Life

Sugars in breast milk are essential for the development of the newborn immune system and the growth of beneficial commensal bacteria in the gut. But certain milk sugars in certain contexts could be bad news.

The team led by Thierry Hennet at the University of Zurich found that newborn mice fostered by mothers lacking one particular milk sugar-sialyl(alpha2,3)lactose-were less susceptible to inflammation-induced colitis later in life.

The resistance to colitis was attributed to differences in the commensal bacteria.

Determining whether this milk sugar has some redeeming qualities-for example in facilitating defense against dangerous intestinal pathogens-will require further studies.

The study was published online on November 22 in the Journal of Experimental Medicine.

Source: ANI

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