Study Says HIV Replication Process Could be Different Than Previously Thought

by Kathy Jones on  July 17, 2010 at 10:19 PM AIDS/HIV News
RSS Email Print This Page Comment
Font : A-A+

A new study says that the process by which a retrovirus, like HIV, reproduces and assembles new viruses is different than previously thought.
 Study Says HIV  Replication  Process  Could be  Different  Than  Previously Thought
Study Says HIV Replication Process Could be Different Than Previously Thought

Researchers at Penn State College of Medicine studied a chicken virus called Rous sarcoma virus that causes cancer in chickens and is similar to HIV.

The start of the replication process is the production by the retrovirus of a protein called Gag.

Prior to this study, it was thought the building process happened outside the nucleus in the cyctoplasm- the material that fills the cell-and then Gag protein was sent to the plasma membrane- the outer boundary of the cell.

However, research revealed that Rous sarcoma virus takes a detour through the cell nucleus before going to the cell membrane.

The Gag protein binds to the viral RNA inside the nucleus, causing alteration in the structure of the protein.

"If we interfere with the first step, the virus will never be released from the cell. Cells are complex, so we use the key elements in a test tube to figure out how Gag and the RNA interact," said Leslie Parent, M.D., Ph.D., professor of infectious diseases, department of medicine.

Source: ANI

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Oral Health And AIDS AIDS/HIV AIDS/HIV - Epidemiology AIDS/HIV - Clinical Features AIDS/HIV - Health Education AIDS/HIV - Prevention And Transmission AIDS / HIV - Treatment AIDS/HIV- Lab Tests and Faqs Prostitution: Fresh Stakes in the Oldest Trade HIV Symptom 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive