Study Says Children Inherit Diabetes from Parents

by Rajashri on  August 22, 2008 at 4:38 PM Genetics & Stem Cells News   - G J E 4
 Study Says Children Inherit Diabetes from Parents
A new study has found that diabetes is an inherited condition.

Researchers suggest that unusual form of inheritance might play a role in the increasing rates of diabetes, especially in children and young adults.

The research team is currently studying the metabolic programming, which occurs when an insult during a critical period of development, either in the womb or soon after birth, triggers permanent changes in metabolism.

In the present study conducted using a mouse model the team looked at the effects of a diet high in saturated fat on mice and their offspring.

The results showed that a high-fat diet induced type 2 diabetes in the adult mice and that this effect was reversed by stopping the diet.

However, if female mice continued a high-fat diet during pregnancy and/or suckling, their offspring also had a greater frequency of diabetes development, even though the offspring were given a moderate-fat diet.

These mice were then mated with healthy mice, and the next generation offspring (grandchildren of the original high-fat fed generation) could develop diabetes as well.

They found that exposing a fetal mouse to high levels of saturated fats can cause it and its offspring to acquire diabetes, even if the mouse goes off the high-fat diet and its young are never directly exposed.

The study will be published in the September issue of the Journal of Lipid Research.

Source: ANI

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