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Study Reveals New Causes Behind Severe Childhood Obesity

by VR Sreeraman on  December 7, 2009 at 4:16 PM Obesity News   - G J E 4
 Study Reveals New Causes Behind Severe Childhood Obesity
Scientists in Cambridge have found that genetic alteration can lead to severe obesity in childhood.

According to a study published in Nature, the loss of a key segment of DNA may play an important role in genetic diseases.
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Lead researchers Dr Sadaf Farooqi from the University of Cambridge and Dr Matt Hurles from the Wellcome Trust Sanger Institute examined 300 kids with severe obesity.

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Dr Farooqi said: "We found that part of chromosome 16 can be deleted in some families, and that people with this deletion have severe obesity from a young age.

"Our results suggest that one particular gene on chromosome 16 called SH2B1 plays a key role in regulating weight and also in handling blood sugar levels. People with deletions involving this gene had a strong drive to eat and gained weight very easily."

Dr Matt Hurles added: "This is the first evidence that copy number variants have been linked to a metabolic condition such as obesity. They are already known to cause other disorders such as autism and learning difficulties."

Source: ANI
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