Study Points to the Benefit of Diabetes Drug in Fighting Lung Cancer in Mice

by Savitha.C.Muppala on  September 02, 2010 at 4:37 PM Cancer News
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Dr Michael Pollak, professor of medicine and oncology at McGill University said the "important laboratory study, together with prior laboratory and epidemiology research, suggest that metformin may be useful in cancer prevention and treatment.

"There is new information available about the mechanisms by which this drug, which is based on compounds present in lilac, may be useful for cancer control," Pollak said.

Studies conducted in Britain in 2005 showed that diabetics who took metformin had a 40-percent lower risk of cancer compared with diabetics who did not take the drug, Pollak told a news conference.

Other laboratory studies have found that metformin can block the growth of many, but not all, cancer cells by targeting their energy intake, Pollak said.

Metformin was approved by the US drug safety regulator, the FDA, for the treatment of type two diabetes in 1995. As of 2008, 40 million people in the United States took metformin.

The deadliest of all cancers, lung cancer claims nearly eight million lives a year.

It is also the fastest-growing form of cancer with more than 12 million new cases diagnosed annually.

Source-AFP
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