Study Emphasizes the Need for Colorectal Cancer Screening at 50

by Sreeraman on  September 04, 2008 at 4:38 PM Cancer News
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A new study has suggested that screening for colorectal cancer screening should start at age 50.

In the study, researchers at the John Hopkins University found that colorectal adenomas - the precursor polyps in virtually all colorectal cancers - occur infrequently in younger adults but the rate sharply increases after age 50.

Therefore, the researchers emphasize the importance of colonoscopies, which view the entire colon, for the prevention of colorectal cancer beginning at age 50.

"While colorectal polyps are rare in adults aged 30 to 50, our study reveals an increase in polyp prevalence with age and a dramatic increase in colorectal adenoma incidence occurring in adults over the age of 50," said Francis M. Giardiello, MD, of The John Hopkins University and lead author of the study.

"Understanding the natural occurrence of colorectal polyps, especially in younger adults, is important to the development of colorectal cancer prevention strategies," Giardiello added.

During the study, researchers found that the prevalence of colorectal polyps in younger adults increased from 1.72 percent to 3.59 percent from age 30 to 50.

This rate sharply increased after age 50 with the prevalence of polyps ranging from 10.1 to 12.06 percent in the sixth and ninth decade, respectively. The study results quantified the number of adenomas typically found in people under the age of 50.

The researchers said that it is important to note that those with two or more adenomas under 50 years of age represent unusual individuals who might merit closer colonoscopic surveillance for subsequent adenoma development.

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