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Studies on Potentially Serious Manifestations of Acid Reflux
October 19, 2007 at 1:01 PM
General Health News
Researchers at the Medical University of South Carolina in Charleston studied a group of patients with persistent cough who took acid-suppression therapy (proton pump inhibitors) over a period of three years to evaluate the cost-effectiveness of MII-pH, a device that can detect reflux without depending on the acidity of the contents that refluxes into the esophagus. Unlike conventional pH monitoring, which measures acidity, this new technique can detect non-acid reflux.
Researchers used a cost-utility analysis to evaluate the cost-effectiveness of this diagnostic intervention among patients on high dose PPI therapy with chronic persistent cough who might be candidates for anti-reflux surgery, such as laparoscopic fundoplication. Researchers included costs of medication use, physician visits and surgery in their model.
According to Dr. Deepika Koya, “The use of MII-pH testing in patients who experience reflux of non-acid stomach contents is cost-effective by helping clinicians determine which patients would benefit from anti-reflux surgery and excluding those for whom surgery may have no benefit. This warrants further evaluation of widespread application of MII-pH testing in the diagnosis of patients with persistent chronic cough on adequate medical therapy.”
Source-Eurekalert
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