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Steroid Hydrocortisone No Use to Premature Babies: Johns Hopkins Children’s Center
Researchers claimed that such treatment doesn’t offer much benefit and also low cortisol levels are not even necessarily harmful.
On the other hand, high cortisol levels, apparently increase the risk of dangerous bleeding in the brain and it is required that babies should be monitored aggressively to ward off life-threatening complications.
Premature babies and adults having a condition, called relative adrenal insufficiency, have abnormally low levels of the stress hormone cortisol and it is usually treated by hydrocortisone therapy in the newborns.
The new findings, however, shed new light on the clinical meaning of low cortisol levels in preemies. It shows that contrary to common belief, low blood concentrations of this hormone do not put extremely low-birth-weight babies (those born weighing less than 2.2 pounds) at higher risk for retinopathy of prematurity — a potentially blinding eye condition — inflammation and lung disease.
No difference was found in health outcomes between babies with low cortisol levels who were treated with hydrocortisone and those given a placebo.
While hydrocortisone didn’t have adverse effects on a baby’s health, it also did nothing to prevent or reduce respiratory diseases, infections, hemorrhages or retinopathy.
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