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Stem Cells Found in the Pituitary
They also found that these stem cells are different from the majority of adult stem cells that trigger the initial growth of this important organ.
The results of the study also suggest a novel way that can be taken up by the pituitary gland in both adolescents and adults, to traumatic stress or to normal life changes like pregnancy.
Earlier, Grigori Enikolopov, Ph.D., an associate professor at Cold Spring Harbor Laboratory (CSHL), had known that a gene called Nestin was active in neural stem cells and they had genetically engineered mice so that the same conditions that activate Nestin in a particular cell also make it glow green under ultraviolet light. After that many such teams have used these special mice to help find adult stem cells in hair follicles, liver, muscle, and other tissues.
The pituitary gland in humans is about the size of a pea and sits at the base of the brain, where it secretes hormones that regulate various processes throughout the body. However, in mice, the gland develops in the embryo, but then has a second growth spurt.
Anatoli Gleiberman, Ph.D., a researcher in the lab of pituitary expert M. Geoff Rosenfeld at the University of California, San Diego, in collaboration with Grigori Enikolopov, aimed to look for pituitary stem cells.
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