In the iPS work, it has been tested successfully on mouse and human skin cells. Tests on the reprogrammed cells lines show they faithfully reproduce the behaviour of embryonic stem cells.
"I was very excited when I found stem cell-like cells in my culture dishes. Nobody, including me, thought it was really possible," said Keisuke Kaji from the Centre for Regenerative Medicine at the University of Edinburgh, Scotland.
In a press release issued by Britain's Medical Research Council, Ian Wilmut, the "father" of Dolly the cloned sheep, stressed that the new iPS cells would have to be tested thoroughly for safety before being used in any human trials.
And, "crucially," scientists were still hunting for a way of coaxing pluripotent cells into the specialised tissues that could be used in transplants, said Wilmut, who heads the unit where Kaji works.
Even so, "there is hope that the promise of regenerative medicine could soon be met," he said.
Stem cells have excited huge interest over the past decade. Promoters say this material could reverse cancer, diabetes, Alzheimer's and other regenerative diseases.
But the dynamic has been sapped by opposition from religious conservatives, who argue that research on embryos, the prime source of stem cells so far, destroys human life.
Source-AFP
SRM