Custom Search

Register
Sign In
Sign In Using Facebook

Stem Cell Breakthrough Now Moves A Step Ahead!

by Sreeraman on  March 02, 2009 at 4:08 PM Genetics & Stem Cells News
  •   Print
  •   Share
  •   Comments
  •  Text 
Pioneering work by Japanese stem-cell researchers two years ago has taken a major step forward, helping the quest for versatile, grow-in-a-dish transplant tissue, according to papers published on Sunday.
 Stem Cell Breakthrough Now Moves A Step Ahead!


Two teams have combined ideas to devise a safer technique for reprogramming skin cells so that they become "pluripotent" stem cells, fundamental cells that then grow into specialised organs.

Their effort builds on an award-winning breakthrough in 2007 by Shinya Yamanaka of Kyoto University.

He and his team introduced four genes into skin cells, reprogramming them so that they became indistinguishable from embryonic stem cells.

That achievement conjured the distant vision of an almost limitless source of transplant material that would be free of controversy, as it would entail no cells derived from embryos.

But the downside of the technique for creating these so-called induced pluripotent stem cells (iPS) is that the genes are delivered by a "Trojan horse" virus.

Reprogramming cells using a virus modifies their DNA in such a way that they cannot be given to patients without boosting the risk of cancer.

In the new studies, published by the British-based journal Nature, two squads of researchers from Britain and Canada recount a method by which the four genes are delivered into the cell without using a virus, and then are removed after the reprogramming is done.

The insertion is carried out using "piggyBac," a tried-and-tested technique in genetically-modified crops in which mobile genetic sequences called transposons are slotted into the genome.

Page 1 Page 1 | 2  Next
 Email Email   RSS Feeds RSS Feeds   Print this page Print   Save this page Save   Link Link   Syndicate Syndicate   Comments Comments   Bookmark and Share
 
Comment & Contribute
Be the first to comment!
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions
  

X
  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Archive
Date :
Category :
Keyword :
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
News Categories:  
Diabetes Health Center

Genetics & Stem Cells Related News

» New Prenatal Genetic Test can Detect Fetal Abnormalities in a Better Way Than Existing Tests » Genetics may be Able to Guide Treatment for Tuberculosis
» Fathers Pass on Heart Disease Risk to Sons Via Genetic Variation on the Y Chromosome » Stem Cell Trial for Hearing Loss
» Traces To Common Birth Defect in Gene Expression Data, Noticed by MassGeneral, Jackson Researchers » Reason for the Survival of Bad Immunity Genes
» Eradicating of Genetic Diseases Perhaps Via 'Designer' Babies of 3 Parents » More Accurate Diagnosis of Genetic Mutations Possible Via New Virtual Tool
Read More >>