login
Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
Speed Kills Cancer Cells
November 22, 2007 at 7:05 PM
Cancer News
And this is possible by using bortezomib, a promising cancer drug, which helps to strike a blow against melanoma tumour cells by revving up the action of a cancer-promoting gene. Researchers discovered that bortezomib, a drug approved by the FDA to treat advanced multiple myeloma, is able to selectively inhibit melanoma tumour cells because it causes the c-MYC oncogene to overproduce a cell-death promoter called NOXA.
Their findings place c-MYC and NOXA, well studied among cancer researchers, in a new light. Our data suggest a different approach to treat cancer, said Maria S. Soengas, Ph.D., the senior author of the study. Many cancer treatments aim to block specific oncogenes, genes that wreak havoc with the normal signals that dictate when cells multiply and die.
The thinking is that if oncogenes are disabled, cancer cells cant proliferate uncontrollably and spread. However, researchers know that oncogenes can play dual roles: They can cause tumour cells to rapidly divide, but can also step up programmed cell death, or apoptosis. Therefore, an alternative treatment could be to actually exacerbate oncogene function, to promote such a dysregulation of cell cycle progression and activation of apoptotic proteins that tumour cells ultimately die, Soengas said.
|
|
|
 Comment & Contribute
|
Medwonders Health Network
- Health News Index
 | Quiz on Cancer Looking for information on cancer? Go through medindia's Cancer quiz. 
|
- News Quick Links
 |
Cancer
Complete Medindia Resources
|
| News Categories: |
| » | Report: A Lot of Americans Have No Access to Health Care |
| » | Greece Faces Humanitarian Crisis as Health Care Access Declines in EU, Doctors Group Warns |
| » | HCCI Report Says Rising Prices for Care Responsible for Increased Healthcare Costs for Privately Insured Americans |
| » | Treatment in ED is Based on Children's Insurance Status |
| » | US Spends Most on Healthcare Without Providing Superior Care |
| More Insurance News | |
|
