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Spanish Flu Records hold Key to Prevent Future Pandemics
The researchers are analysing UK data from the three waves of the pandemic in 1918 and 1919.
They hope that modern high-speed computing and mathematical modeling techniques will help them solve some of the questions about the pandemic which have puzzled scientists for close to a century.
Professorial Fellow John Mathews and colleagues are analysing the records of 24,000 people collected from 12 locations in the UK during the Spanish flu outbreak including Cambridge University, public boarding schools and elementary schools.
He said that gaining a better understanding of how and why the virus spread will help health authorities make decisions about how to tackle future pandemics.
"In the 1918/19 pandemic, mortality was greatest among previously healthy young adults, when normally you would expect that elderly people would be the most likely to die. We don't really understand why children and older adults were at lesser risk," Mathews said.
"One explanation may be that children were protected by innate immunity while older people may have been exposed to a similar virus in the decades before 1890 which gave them partial but long-lasting protection.
"Those born after 1890 were young adults in 1918. They did not have the innate immunity of children and as they weren't exposed to the pre-1890 virus they had little or no immunity against the 1918 virus. We can't prove it but it is a plausible explanation," he added.
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