Medindia On Mobile
Custom Search

Register
Sign In
Sign In Using Facebook
HOME NEWS HEALTH A-Z HEALTH CENTRES HEALTH TOOLS DIRECTORIES SERVICES WEBSITES BUY ONLINE BLOGS COMMUNITY DOWNLOADS
Home » Genetics & Stem Cells News

Singapore Scientists Find Gene That Improves Quality of Reprogrammed Stem Cells

by Rajshri on  February 08, 2010 at 9:04 PM Genetics & Stem Cells News
  •   Print
  •   Share
  •   Comments
  •  Text 
Singapore Scientists Find Gene That Improves Quality of Reprogrammed Stem Cells
Scientists at the Genome Institute of Singapore (GIS), report that a genetic molecule, called Tbx3, which is crucial for many aspects of early developmental processes in mammals, significantly improves the quality of stem cells that have been reprogrammed from differentiated cells. They report these findings in the 7 Feb. 2010 issue of the journal Nature


Stem cells reprogrammed from differentiated cells are known as induced pluripotent stem cells or iPS cells.

By adding Tbx3 to the existing reprogramming cocktail, GIS scientists successfully produced iPS cells that were much more efficient in recapitulating the entire developmental process.

The capability of iPS cells for germ-line transmission represents one of the most stringent tests of their ESC-like quality. This test requires that iPS cells contribute to the formation of germ cells that are responsible for propagating the next generation of offspring.

"This represents a significant milestone in raising the current standards of iPS cell research. With this new knowledge, we are now able to generate iPS cells which are, or approach, the true equivalent of ESCs," said Lim Bing, M.D., Ph.D., lead author of the Nature paper and Senior Group Leader at GIS, one of the research institutes of Singapore's A*STAR (Agency for Science, Technology and Research).

"When applied to the area of cell therapy-based medicine, we have a better inkling of what we might aim for before differentiating iPS cells to clinically useful cell types. The finding also adds to our insight into the fascinatingly, unchartered but rapidly moving field of reprogramming," Lim added.

Page 1 Page 1 | 2  Next
 Email Email   RSS Feeds RSS Feeds   Print this page Print   Save this page Save   Link Link   Syndicate Syndicate   Comments Comments   Bookmark and Share
 
More News on: DNA Finger Printing, Stem Cells - Cord Blood, Stem Cells - Fundamentals, Genetics and Stem Cells, Parkinsons Disease Surgical Treatment
Comment & Contribute
Be the first to comment!
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions 		  

X

Medwonders Health Network

Total Members - 54731
Support Groups - 445
Login  Join Now
Medwonders Health Network
  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Archive
Date :
Category :
Keyword :
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
News Categories:  
Senior Health Center
Follow us on : YouTube on Medindia.net Facebook on Medindia.net Twitter on Medindia.net Googleplus on Medindia.net Tumblr on Medindia.net RSS Iphone Digg on Medindia.net Stumbleupon on Medindia.net Delicious on Medindia.net

Consumers

Online Consults Child Health Teen Health Men's Health Women's Health Senior Health Sexual Health Mental Health Dental Health Kidney Health
Diabetes Obesity Vision Care Diet & Nutrition Know Your Body Amazing Body Facts Health Facts Conditions by Specialties Disease FAQs Medical Humour

Medical Professionals

Clinical Tools Health Videos Animation Slides Medical Aphorism Medical Conferences Jobs Journals Web Journals Open Access E-articles
Distance education Doctors Homepage Hospitals Homepage Personalize Info Matrimonial Print Oath Alumni Medical Humour Buy Books

Medical Students

Admissions Medical Colleges Medical Electives Medical Aphorism Post Grad Courses Indian Universities USMLE Centers CGFNS Centers
FRCS in UK PLAB USMLE CGFNS Alumni MCQ Bank Medical Humour Buy Books

Directories

Doctors Hospitals International Hospitals Chemists Surgical Suppliers NGOs Pharmaceuticals Medical Colleges
Home About us Career Sitemap Press Portfolio Advertise Contact Us
Disclaimer - The contents of this site are for informational purposes only. Always seek the advice of a qualified physician for any doubts.
Advertise with us Medindia Copyright Privacy Policy Terms of Use © All Rights Reserved 1997 - 2012