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Simple Fluorescence Test to Check for Urinary Tract Infections in Near Future
Developed by Macquarie University researchers, this unique fluorescence test holds the potential to provide warnings about the presence of other disorders and diseases including cancer.
According to researcher Professor Ewa Goldys, of the university's Department of Physics, the research could lead to a home diagnosis kit that uses simple technology now available.
She pointed out that the impact of urinary tract infections is underestimated till date. Causing about 60 in 1000 patient consultations annually, UTIs are estimated to account for 30 to 40 percent of all hospital-acquired infections.
In the study, the researchers analysed 70 urine samples and found that there exists a clear variation in the fluorescence levels at certain wavelengths in normal and bacteria-infected urine.
They said that this difference is caused due to the presence of bacteria that makes the body to respond by increasing levels of the enzyme indoleamine dioxygenase (IDO), which aids in fighting off infection by reducing levels of tryptophan, an amino acid that promotes microbial growth.
Goldys said that even though urinary tract infections can be easily treated with antibiotics, there needs to be a rapid and inexpensive form of diagnosis to avoid the condition to deteriorate further.
While the current method used for confirming a urinary tract infection is via chemical analysis of a urine sample, which may take 24 hours to be available, the fluorescence test requires a light detector and light source to view the urine sample.
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