A new research from the University of Pennsylvania School of Medicine has revealed an increased incidence of major adverse cardiac events (MACE) in patients with severe psoriasis.
Psoriasis is a common inflammatory skin disease, and if severe, has been demonstrated to be a risk factor for cardiovascular (CV) disease. However, the degree to which psoriasis is associated with MACE, such as heart attack, stroke, and cardiovascular death has not been defined.
In a cohort study analyzing data from a general practice research database, they found that patients with severe psoriasis have a 53 percent increased incidence of MACE compared to the general population.
They also found that having a diagnosed case of severe psoriasis confers an additional ten-year risk of 6 percent on MACE.
The study results were reported at the 2011 American College of Cardiology meeting in New Orleans.