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Scientists Transform Thymus Cells into Skin Cells
The findings show that these stem cells change their genetic make-up according to their environment to contribute to the long-term functioning of the skin, even producing hair for up to a year after implantation.
In collaboration with the University of Edinburgh, UK, the Swiss research team with European colleagues isolated thymic epithelial cells (TECs)-taken from the thymus of a rat-and integrated them into the rat's skin cells with surprising results.
These epithelial cells taken from the thymus, an organ found in the thoracic cage, switch over from what they were originally created by the body to do and take up a novel role according to their new environment.
"These cells really change track, expressing different genes and becoming more important," Nature quoted Professor Yann Barrandon, head of the Laboratory Stem Cell Dynamics, as saying.
While in the thymus, these cells teach T-cells to recognize and destroy bacteria and cancer cells-a key component to the immune system.
The results show that these cells have the ability to express genetic markers unlike its original make-up when placed in different microenviroments.
Until now, experiments using hair follicle stem cells to maintain hair and skin growth have met with limited results.
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