"The machine sits in your home and when it's time for you to take your medication, it makes a beeping noise. If you don't hit a button after about five minutes, it's going to beep louder and louder until you come. If you don't come after a certain amount of time, the machine can call the clinical trial coordinator and indicate that subject or patient didn't take the medication as prescribed," Melker said.
The device is slightly smaller than a shoebox, and has been programmed to record the results of each breath test.
Melker said that this would allow patients to bring a memory card or USB key to the clinic once a month, and receive a printout of their results.
He envisions that the size of the detection device will one day be reduced to such an extent that it would be ready to be fit into a mobile phone.
He, however, insists that the current device also works satisfactorily.
"The doctor can see how often you took it and exactly what time. If it made the patient really sick or dizzy and they didn't take it, they can find out why. It's not just a question of did I or didn't I take it, but when you took it or why you didn't take it," Melker said.
The makers of the device say that it may also be used to monitor medication adherence in patients with other communicable diseases, like tuberculosis.
"If we had a good way of doing DOT that's realistic, instead of having someone come to your house or you going to clinic every day of your life, then we would know whether these people stopped taking their medication and why. Right now, nobody knows any of that." Melker said.
"The implications of being able to understand what normal human behaviour is in a clinical trial and, of course, in the real world, are huge," he added.
Source-ANI
KAV/L