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Scientists Make Significant Discoveries in Mosquitoes and Malarial Parasite
The parasite dispatches hundreds of so-called "effector" proteins into the blood cell's cytoplasm, modifying the cell and masking the invader from the immune system.
One of the primers for this is an enzyme called Plasmepsin V.
"Plasmepsin V is responsible for determining that all the hundreds of effector proteins are exported. If we could find drugs to block Plasmepsin V, the malaria parasite would die," said Alan Cowman of the Walter and Liza Hall Institute in Melbourne.
There were 247 million cases of malaria in 2006, causing nearly one million deaths, according to the World Health Organisation (WHO) website. Most of the fatalities were African children.
Countries that have widespread incidence of malaria are also hit economically, losing as much as 1.3 percent of their gross domestic product (GDP), says the WHO.
Source-AFP
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