20 genes associated with osteoporosis and bone weakness, including 13 genes never previously associated with the disease, have been identified by researchers at Jewish General Hospital in Montreal.
Osteoporosis is a highly heritable trait, but this marks the largest international effort to conclusively identify genes linked to the often-devastating bone disorder.
The study's co-first author is Dr. J. Brent Richards of the Lady Davis Institute for Medical Research at the Jewish General Hospital in Montreal, who collaborated with more than 30 co-authors worldwide.
The results were published recently in the journal Nature Genetics.
The researchers reviewed data collected from nearly 20,000 individuals in five recent international genetic studies.