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Scientists Have Identified the Gene That Influences Height
However, the difference in height between a person carrying 2 copies of the gene and a person carrying no copy of it is only 1 cm.
Yet, the scientists think that the discovery is quite significant.
Previous studies have suggested that, unlike conditions such as obesity, which is caused by a mix of genetic and environmental factors so called "nature and nurture" 90pct of normal variation in human height is due to genetic factors rather than, for example, diet. However, other than very rare gene variants that affect height in only a small number of people, no common gene variants have until now been identified.
The research was led by Dr Tim Frayling from the Peninsula Medical School, Exeter, Professor Mark McCarthy from the University of Oxford and Dr Joel Hirschhorn from the Broad Institute of Harvard and MIT in Cambridge, US. Dr Frayling and Professor McCarthy were also part of a Wellcome Trust-funded study team that discovered the first common gene linked to obesity in April this year.
Using data from the Wellcome Trust Case Control Consortium, the largest study ever undertaken into the genetics underlying common diseases, and the Diabetes Genetics Initiative, in the US, the researchers conducted a genome-wide study of DNA samples from 5,000 people. The findings that variations in the gene HMGA2 make some people taller than others.
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