Scientists of the Princeton University have
discovered a mechanism involved in the spread of breast cancer to bones.This
discovery might lead to new treatment for the disease.
Often cancer cells travel throughout the body. This can cause new tumors in a
patient with advanced breast cancer. This happens in about 70-80% cases. It can
spread not only to the bones but also the brain, lung and liver. The process is
called metastasis and commonly results in formation of malignant bone tumors. The
new study has discovered the exact mechanism that allows the traveling of the
tumor cells that disrupt normal bone growth.
In cancer patients the relationship between signaling molecules and the
molecules that communicate the signal is disrupted. This cell signaling leads
the breast tumor cells to give wrong instructions to the bone cells. The signaling
process involves a pathway with groups of molecules that work together. The
researchers found that this pathway is disrupted in case of metastatic breast