Medindia

X

Scientists Discover How Body Cells can be Put to Use to Regenerate Heart Muscles

by Savitha C Muppala on  August 9, 2010 at 11:09 AM Heart Disease News   - G J E 4
Scientists at the Gladstone Institute of Cardiovascular Disease (GICD) have found how the body cells can be used to regenerate heart muscles.
 Scientists Discover How Body Cells can be Put to Use to Regenerate Heart Muscles
Scientists Discover How Body Cells can be Put to Use to Regenerate Heart Muscles
Advertisement

GICD director Deepak Srivastava and colleagues were able to directly reprogram heart cells called fibroblasts to become beating heart cells called cardiomyocytes.

Advertisement
The study was successful in mice hearts and so, could have therapeutic implications.

"Scientists have tried for 20 years to convert nonmuscle cells into heart muscle, but it turns out we just needed the right combination of genes at the right dose," said Dr. Masaki Ieda.

"Introducing the defined factors, or factors that mimic their effect, directly into the heart to create new heart muscle would avoid the need to inject stem cells into the heart and all the obstacles that go along with such cell-based therapies," Ieda added.

This method also eliminates the risk that some stem cells might develop inappropriately to form tumours.

However, additional work will be necessary to refine the method and bring it closer to a practical therapeutic strategy.

The study is published in the current issue of Cell.

Source: ANI
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All