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Scientists Create New Mouse Model for Peanut Allergy

by Savitha on January 14, 2009 at 4:27 PM Research News

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"The history between S. aureus and allergic diseases led us to use staphylococcal toxins to stimulate food allergy in animals," he added.

The researchers showed that the SEB/WPE mixture stimulated severe symptoms in mice that closely resemble those found in human anaphylaxis, including swelling around the eyes and mouth, reduced movement and significant problems breathing.

Additionally, mice given the SEB/WPE mixture had high blood levels of histamine, which indicates a severe allergic reaction.

The study appears in the Journal of Allergy and Clinical Immunology.

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