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Scientists Closer to Cracking the Autoimmune Mystery
September 06, 2007 at 11:52 AM
Research News
"The capacity to explore the human genome has reached the worker bee," says John Harley of the Arthritis and Immunology Research Program at the Oklahoma Medical Research Foundation in Oklahoma City. "It has filtered down far enough that we now have the capacity to do experiments we only dreamed of 10 years ago."
Now, he says, "the whole range of human disease is going to be studied using this approach and will produce new clues that will be utterly transforming in our ability to manipulate the fundamental disease process."
Disorders of the immune system can be debilitating and expensive, and are likely to be much more common than previously realized. But just how many people have them is not known, because such diseases are not tracked. The National Institutes of Health estimated in a 2005 report that 5% to 8% of Americans, up to 23.5 million, have one or more autoimmune diseases, which occur when the immune system launches an attack on healthy cells within its own body.
In the current issue of the Journal of Clinical Immunology, researchers estimate, based on a random telephone survey, that another group of immune disorders called primary immune deficiency diseases may afflict as many as one in 1,200. In these diseases, caused by an inborn genetic defect, the body can't mount an effective immune response to infection.
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More News on: Myasthenia Gravis, Vitiligo, Autoimmune Disorders, Wegener’s Granulomatosis, Microscopic Polyangiitis
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